ABSTRACT
Background: The outbreak of the new coronavirus disease 2019 (COVID-19) is majorly threatening the health of people worldwide. Since patients with chronic diseases, including diabetes mellitus (DM), are among the main groups at risk of severe COVID-19;hence, this study was aimed to investigate the mortality rate of COVID-19 among patients with DM. Material(s) and Method(s): This cross-sectional study was performed on 211 DM patients with COVID-19 who were referred to Educational Kowsar Hospital in Semnan, Iran. After a definitive diagnosis of COVID-19, basic characteristics, including gender, weight, height, and clinical information (such as initial signs and symptoms, underlying diseases, complications during hospitalization, and type of treatment received) were collected. Result(s): The mean age of patients was 64.92+/-12.7 years, and 51.7% were male. Totally 20.9% of patients were expired. The most frequent underlying diseases were hypertension and ischemic heart disease. The simultaneous presence of cardiovascular diseases in DM patients with COVID-19 was correlated with a considerable mortality rate increment. Cough on arrival significantly predicted mortality reduction to less than one-third (P=0.009). Also, oxygen saturation of less than 90% on arrival was a significant predictor of an increase in mortality by more than double (P<0.001). Conclusion(s): According to the results of multivariate logistic regression, it was found that DM can increment the probability of contracting COVID-19, and the rate of mortality was also higher in these patients.Copyright © 2022, Galen Medical Journal.
ABSTRACT
Background: The outbreak of the new coronavirus disease 2019 (COVID-19) is majorly threatening the health of people worldwide. Since patients with chronic diseases, including diabetes mellitus (DM), are among the main groups at risk of severe COVID-19;hence, this study was aimed to investigate the mortality rate of COVID-19 among patients with DM. Materials and Methods: This cross-sectional study was performed on 211 DM patients with COVID-19 who were referred to Educational Kowsar Hospital in Semnan, Iran. After a definitive diagnosis of COVID-19, basic characteristics, including gender, weight, height, and clinical information (such as initial signs and symptoms, underlying diseases, complications during hospitalization, and type of treatment received) were collected. Results: The mean age of patients was 64.92 +/- 12.7 years, and 51.7% were male. Totally 20.9% of patients were expired. The most frequent underlying diseases were hypertension and ischemic heart disease. The simultaneous presence of cardiovascular diseases in DM patients with COVID-19 was correlated with a considerable mortality rate increment. Cough on arrival significantly predicted mortality reduction to less than one-third (P=0.009). Also, oxygen saturation of less than 90% on arrival was a significant predictor of an increase in mortality by more than double (P<0.001). Conclusion: According to the results of multivariate logistic regression, it was found that DM can increment the probability of contracting COVID-19, and the rate of mortality was also higher in these patients. [GMJ.2022;11:e2590] DOI:10.31661/gmj.v11i.2590
ABSTRACT
Introduction: Statins are a group of lipid-lowering medications that have anti-inflammatory and immune system-modulating effects. Considering the existence of severe inflammatory reactions in patients with covid-19, this study aimed to investigate the effects of statins on the mortality rate of covid-19 patients. Material(s) and Method(s): The present research is a descriptive-analytical case-control study that was carried out in the first half of 2021 at Kowsar Hospital in Semnan, Iran. The study was conducted on 191 patients taking statins as the case group and 191 patients with no history of taking statins. Demographic and clinical information of the patients who met the inclusion criteria of the research were extracted from the files and collected in the researcher's questionnaire. Finally, the results were statistically analyzed using SPSS software version 26. Result(s): In this study, a case group of 191 people, who had a history of taking statins, and a control group of 191 people, who did not use statins, were investigated. The average age of people was 64.7 years. Among the studied patients, 51.7% were men and 48.3% were women. Most of the patients were hospitalized for 4 days. Also, 351 patients were discharged and 32 people died. After analyzing the data, no significant relationship was observed between the use of statin and mortality due to Covid-19. Discussion and Conclusion(s): According to the results of this study, no relationship was observed between the use of statins and the reduction of mortality caused by covid-19. Copyright © 2022 Wolters Kluwer Medknow Publications. All rights reserved.
ABSTRACT
Introduction: Statins are a group of lipid-lowering medications that have anti-inflammatory and immune system-modulating effects. Considering the existence of severe inflammatory reactions in patients with covid-19, this study aimed to investigate the effects of statins on the mortality rate of covid-19 patients.Materials and Methods: The present research is a descriptive-analytical case-control study that was carried out in the first half of 2021 at Kowsar Hospital in Semnan, Iran. The study was conducted on 191 patients taking statins as the case group and 191 patients with no history of taking statins. Demographic and clinical information of the patients who met the inclusion criteria of the research were extracted from the files and collected in the researcher's questionnaire. Finally, the results were statistically analyzed using SP SS software version 26.Results: In this study, a case group of 191 people, who had a history of taking statins, and a control group of 191 people, who did not use statins, were investigated. The average age of people was 64.7 years. Among the studied patients, 51.7% were men and 48.3% were women. Most of the patients were hospitalized for 4 days. Also, 351 patients were discharged and 32 people died. After analyzing the data, no significant relationship was observed between the use of statin and mortality due to Covid-19.Discussion and Conclusion: According to the results of this study, no relationship was observed between the use of statins and the reduction of mortality caused by covid-19.